19. Kirstie Alley is the only main character of Cheers who didn’t appear on Frasier.
Throughout Frasier’s long run on TV, Kirstie Alley was the only one of the main cast of Cheers not to make an appearance on the show.
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“Kirstie once said … she’d never do a show about a psychiatrist,” Kelsey Grammer said in 2002.
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Possibly because of her ties to Scientology.
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